Recent research shows a surprising link between blood type and stroke risk. People with blood type A1 may face a higher chance of stroke before turning 60. This discovery offers fresh insight into how genetics affect our health.
Most people know the common blood types: A, B, AB, and O. These are defined by antigens on red blood cells. However, smaller subgroups also exist. These subtle differences may explain why some people face more risk than others.
What the Research Found
Scientists reviewed 48 genetic studies. These included data from 17,000 stroke patients and nearly 600,000 people without stroke. Participants were between 18 and 59 years old. Results showed a clear link between the A1 subgroup and early stroke risk.
People with blood type A1 had a 16% higher risk of stroke before 60. By contrast, those with blood type O1 had a 12% lower risk. Interestingly, the increased risk did not appear in people over 60. Therefore, younger strokes may have different causes.
Why Blood Type Matters
Experts believe clotting factors may play a role. Platelets, vessel linings, and proteins all affect clot formation. These may explain why certain blood types carry more risk.
Still, doctors stress that the increased risk is small. “We still don’t know why blood type A carries higher risk,” said Dr. Steven Kittner, vascular neurologist. “More research is needed to understand the mechanism.”
Each year, nearly 800,000 Americans suffer a stroke, most after age 65. As a result, lifestyle choices remain crucial. Staying active, eating healthy, and managing blood pressure are still the best ways to lower risk.