DMT Shows Promise in Healing the Brain After Stroke
A psychedelic molecule is showing remarkable healing potential. Scientists have found that DMT, a natural compound found in plants and even the human brain, can help repair stroke damage.
Researchers at HUN-REN Szeged Biological Research Centre and Semmelweis University discovered that DMT dramatically reduces brain injury in both animal and cell studies. The findings, published in Science Advances, could lead to a new way to improve recovery after stroke.
How DMT Protects the Brain
DMT, or dimethyltryptamine, works by repairing the brain’s blood-brain barrier, which often breaks down after a stroke. “We found that DMT significantly reduced brain swelling and tissue damage,” explained researcher Marcell László.
The team also discovered that DMT lowers inflammation by reducing the activity of immune cells and microglia in the brain. It acts through Sigma-1 receptors, helping nerve cells communicate and heal more effectively.
Co-author Mária Deli added, “It’s fascinating how nature continues to offer solutions for human health.”
A New Hope for Stroke Treatment
Currently, stroke therapies are limited and don’t always lead to full recovery. However, DMT could change that. “Its dual action—protecting the blood-brain barrier and reducing inflammation—makes it a strong candidate to complement existing treatments,” said Judit Vigh, co-first author.
Clinical trials are now exploring DMT’s potential in humans. If results hold, this natural compound could revolutionize how we treat and recover from strokes.
