Shingles Vaccine May Protect Against Dementia and Heart Disease
The shingles vaccine offers benefits that extend well beyond preventing a painful rash. New research presented at IDWeek 2025 reveals that the vaccine may also protect long-term brain and heart health. In a study involving more than 38,000 adults across the United States, researchers found that people who received the shingles vaccine had a lower risk of vascular dementia, stroke, heart attack, and blood clots. Experts believe this protection comes from the vaccine’s ability to reduce inflammation, which plays a key role in damaging blood vessels and nerve cells. By controlling inflammation early, the vaccine may help the body maintain healthier heart and brain function over time. Dr. Ali Dehghani from Case Western Reserve University explained that vaccines not only prevent infections but also influence how the immune system responds to inflammation, which can impact long-term health.
Shingles Vaccine Shows Strong Protection
The study revealed impressive numbers. Those vaccinated had a 50 percent lower risk of vascular dementia, a 25 percent lower risk of heart attack or stroke, and a 27 percent lower chance of developing blood clots. They were also 21 percent less likely to die during the research period. These results suggest that the shingles vaccine may do more than protect against a viral infection—it could also improve survival rates. According to Dr. Manisha Parulekar of Hackensack University Medical Center, the findings bring cautious optimism. She said the vaccine’s anti-inflammatory effect might help prevent cognitive decline and protect brain function.
Experts Call It a New Step in Preventive Care
Dr. Cheng-Han Chen from MemorialCare Saddleback Medical Center added that the vaccine’s ability to control inflammation may protect multiple organs, including the heart and brain. While more research is needed, experts now encourage adults aged 50 and older to get vaccinated, as it may support both cardiovascular and cognitive health for years to come.
