Scientists Find Protein That Rejuvenates the Aging Immune System
Aging affects more than hair color or muscle strength. It also weakens the immune system over time. Now, scientists have discovered a protein that can help aging immune cells act young again.Researchers at the University of Illinois Chicago led the study. Their findings appeared in the journal Blood.
Immune System Changes With Age
The body relies on blood stem cells to create immune cells. These stem cells live in bone marrow. When people are younger, these cells stay balanced and efficient.However, aging changes how these stem cells behave. They begin producing fewer infection-fighting cells.
As a result, older adults face higher risks from illness and inflammation.The researchers focused on a protein called platelet factor 4. In young bodies, it helps control stem cell growth.For example, it prevents certain blood cells from multiplying too quickly.With age, immune cells release less platelet factor 4. Therefore, stem cells divide more often than they should. This increase can lead to mutations and raise disease risk.
Rejuvenating Aging Stem Cells
The team tested what happens when platelet factor 4 returns. They gave older mice daily doses of the protein. After one month, the animals showed younger-looking blood and immune cells.In addition, scientists tested older human stem cells in the lab. The results were similar and encouraging. The protein helped restore healthier immune balance.
This Discovery Means
This protein alone will not stop aging. However, it could support future treatments for immune decline. It may also lower risks tied to blood disorders and inflammation.Most importantly, the study proves aging effects can be reversed at a cellular level. That insight opens new doors for inclusive and healthy aging research.
