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Flavor-Based Chewable Test Offers New Way to Detect Flu

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Flu detection could soon be as simple as chewing gum. Scientists have created a molecular sensor that releases a thyme-like flavor when it encounters the influenza virus. Unlike nasal swabs, this test is quick, inexpensive, and could even identify infections before symptoms begin.

How the Flavor Sensor Works

The research team designed the sensor to release thymol, the compound that gives thyme its strong herbal taste. They attached thymol to a molecule that influenza viruses break down using neuraminidase, the viral glycoprotein. When the virus interacts with the sensor inside the mouth, thymol is released, and the tongue detects the flavor.
In laboratory experiments, the sensor picked up influenza in saliva samples within 30 minutes. Tests on human and mouse cells confirmed that the compound did not interfere with normal cell activity. This makes the method not only simple but also safe.

Why It Could Transform Flu Testing

Current flu tests face clear challenges. PCR swabs are accurate, but they are slow and costly. Rapid at-home tests are cheaper and faster, but they usually miss early-stage infections. People are often contagious before they realize they are sick, which makes prevention difficult.
This new gum-based approach could change that. Chewing gum or sucking on a lozenge may allow people to screen themselves quickly, even before symptoms appear. Early detection means fewer chances to spread the flu to others.
Researchers plan to begin human trials within two years to confirm the effectiveness of the flavor-based sensor. If successful, this innovation could provide a low-tech, widely available screening tool. As a result, chewing gum might one day help control flu outbreaks in schools, hospitals, and workplaces

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