Researchers Warn E-Cigarette Chemicals May Cause Lasting Lung Damage
A new study from the University of California, Riverside, has raised major concerns about e-cigarette safety. Researchers discovered that heating propylene glycol, a common ingredient in e-liquids, creates two harmful chemicals,methylglyoxal and acetaldehyde. These compounds can damage and weaken lung cells over time. As a result, experts now believe e-cigarette use may carry more risks than previously thought.
To explore the effects, scientists used lab-grown human airway tissues. They observed that both chemicals disrupted essential cell functions. However, methylglyoxal proved far more toxic, even at smaller doses. According to study author Professor Prue Talbot, these reactions cause “signs of stress and injury,” which may lead to lasting lung problems with continued vaping.
Methylglyoxal’s strong impact on the lungs
The study found that methylglyoxal harms mitochondria, the cell’s energy source, and damages the actin cytoskeleton that keeps cells strong. This interference can slow cell repair and regeneration, increasing the risk of chronic respiratory diseases. Co-author Man Wong added that low-powered e-cigarettes, often marketed as safer, can actually produce higher levels of methylglyoxal. Therefore, understanding how these toxins form is vital for measuring real vaping dangers.
Even short-term exposure can cause harm
Researchers also found that brief exposure to these chemicals disrupted key processes like DNA repair and energy production. This means even short vaping sessions may trigger harmful cellular changes. Over time, these effects could cause inflammation or chronic lung disease. The study challenges the belief that vaping is a safer choice than smoking. Experts call for more research to define safe exposure limits and guide public health decisions. Until then, users should approach e-cigarettes with caution.
